PSYCH 130 Lecture Notes - Lecture 19: Neuroanatomy, Substance Intoxication, Spatial Navigation
Document Summary
Caused by medical condition, substance intoxication or withdrawal, or toxin. Profound disturbances in sleep/wake cycles: minor neurocognitive disorder. Worsening is a precursor to major neurocognitive disorder: major neurocognitive disorder. 65 is benchmark between early and late onset. Neuroanatomy = atrophy in hippocampus, cingulo-parietal-occipital regions. Genetic polymorphism of gene on chromosome 19 called apoe. Having two of those alleles increases risk for ad. Neuropathology = neurodegeneration caused by amyloid protein plaques neurofibrillary tangles neurons die: frontotemporal dementia. Degeneration can be caused by tau inclusions. Selective degeneration of von econmo neurons found in frontal regions (related to sociality: treatments. Alzheimer"s = aricept prescribed to improve function of nerve cells in brain prevents breakdown of ach. Other meds prescribed to reduce psychological and behavioral symptoms antidepressants, antipsychotics. Neurodegeneration trumps any effects of medications working on meds that arrest neurodegeneration: interventions/prevents. Risk factors related to immune function and cholesterol metabolism live healthy lifestyle: ad vs ftd.
