NUSCTX 103 Lecture Notes - Lecture 7: Active Transport, Oxidative Phosphorylation, Enterocyte

• School: Berkeley
• Department: Nutritional Sciences And Toxicology
• Course: NUSCTX 103
• Professor: Olzmann

Document Summary

Lecture b (professor sul): handling of plasma glucose and glycolysis. Glycogenolysis: breakdown of glycogen (to form gluc) Glycolysis* : breakdown of gluc (to release e & form pyruvate [--> oxidative: what is the flux- generating step in the metabolic pathway of glycolysis phosphorylation & atp synthesis]) Glucose (glucokinase)--> glucose-6-phosphate (dec. amt intracellular glucose = Glut2 can transport more gluc into liver, even when high [glucose]) Commits glc to being metabolized in that cell (g-6-p can"t cross membranes) (flux: rate at which s > p under physio conditions; determined by [plasma gluc] in glycolysis and . Delta g & gnot of enzymes in pathway (predicts directionality) Activity of regulatory enzymes: what is meant by glycolysis and what is its purpose. Breakdown gluc (to pyruvate) w/o using oxygen (anaerobic) to obtain energy (atp) (--> can be further metabolized for energy via kreb"s cycle > oxidative phosphorylation--