NUSCTX 10 Lecture Notes - Lecture 19: Vitamin B6, Fatty Acid Metabolism, Acetaldehyde

• School: Berkeley
• Department: Nutritional Sciences And Toxicology
• Course: NUSCTX 10
• Professor: Chris Vulpeand Robert Ryan

Document Summary

Energy metabolism (part 2) and energy balance: protein metabolism. Loss of amino group from the amino acid. Carbon skeleton is left to enter citric acid cycle (cac: glucogenic amino acids, ketogenic amino acids. Carbon skeleton from the amino acid can give rise to glucose in the liver. Can only enter cac or become ketones: gluconeogenesis. Forming glucose from glucogenic amino acids and other compounds such as glycerol: disposal of excess amino groups. Nitrogen from amino acids is put into ammonia, which is toxic. Adh pathway: 10-30% in stomach and the rest in liver, alcohol converted to acetaldehyde, acetaldehyde converted to acetyl-coa, producing nadh + h+. Coa becomes fatty acids, which is why alcohol can increase fat. Meos: moderate to excessive alcohol, uses energy rather than producing energy. Nutrient interconversions and storage: atp concentrations regulate metabolism. High adp stimulates catabolic reactions: enzymes, hormones, vitamins and minerals are all essential in metabolism.