NUSCTX 10 Lecture Notes - Lecture 17: Niacin, Gestational Diabetes, Iron Supplement
2 Dec 2016
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Document Summary
Adequate amount of nutrients need to be present. Unfertilized egg in ovary fertilized by sperm. Male and female nuclei have genes set aside. Embryo moves down fallopian tube and becomes blastocyst. Forms neural tube and appendages start to butt out. Period of organ genesis is when teratogens are most harmful. Placenta is organ that enables nutrient transfer between mother and child and any metabolic material can be excreted. Hormonal and metabolic changes to support prenatal development and lactation. Increased secretion of cortisol, prolactin, estrogen and progesterone alters energy metabolism. Increased use of fatty acids and anti-insulin effects. Physiological glucose intolerance and insulin resistance to ensure continuous nutrient transport to the fetus via the placenta. Glucose diffuses from mother"s bloodstream to fetus (placenta) Increased levels of ldl, hdl, free fa and utilization of fatty acids and fat deposition. Metabolism switches from using glucose to fatty acids for energy.
