NUSCTX 10 Lecture Notes - Lecture 20: Cortisol, Edema, Homeostasis
2 Dec 2016
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Document Summary
Proteins is 20% of weight of lean tissue. Major structural compartment in bod is bone. Bone is protein (collagen - same protein in scar tissue) and it is calcified. Calcium balances in body influence bone mass and strength and risk of fractures. More in women and increases risk with age. Job is to sense calcium and secrete based on low/high levels. Try to restore/increase availability of calcium in blood. Loses phosphate by kidney and loss of bone calcium. Stimulates ca and p absorption by intestine. Fortified milk or other foods and oily foods. Cortisol affects bone mass in a negative way. Heavier people have greater bone mass than lighter people. Loss of bone mass in some female athletes. Weight bearing activity amenorrhea due to underweight reduce bone mass. Bone mass peaks in women in 20s and 30s and falls thereafter. Interventions can target increasing peak bone mass. Major ions inside cells are k and cl.
