MCELLBI 32 Lecture Notes - Lecture 7: Posterior Pituitary, Adrenal Cortex, Anterior Pituitary
Document Summary
Endocrine system-->includes all the cells and tissues of the body that secrete hormones into the system of the blood stream. Hormones are ligands that bind receptors on or in cells. They can act at distant targets in small concentrations. ->hormones travel throughout the body in the blood. Types of hormones peptide hormones: lipophobic, membrane receptors used to identify e: insulin, acth, oxytocin steroid: lipophilic, use intracellular receptors ex: cortisol amine: lipophobic (epinephrine) or lipophilic (thyroid hormones) ->we will mostly talk about peptides and steroids. ->primary endocrine organs: adrenal gland, hypothalamus, pituitary gland. ->secondary endocrine organs: main job is something else, but has some cells that release hormones. ->tropic hormones: cause the release of other hormones-->regulates the release of other hormones. ->all anterior pituitary are regulated by tropic hormones from hypothalamus. ->gland in the endocrine system, on top of kidney. ->cortisol generated in cortex, goes out into blood. -stress-->hypothalamus-->crh-->anterior pituitary-->acth-->adrenal cortex-->cortisol-->increased fuel in blood, breakdown proteins and use to make atp.