INTEGBI 131 Lecture Notes - Lecture 14: Mast Cell, Endothelium, Megakaryocyte
6 Jan 2020
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Made up of rbc/erythrocytes (45%), platelets & wbc/leukocytes (<1%)- in plasma (55%, liquid/fluid matrix) Function: transport gases, nutrients, hormones, wastes / reg body temp. Volume: m 5-6 l, f 4-5 l. Hematocrit: measure of % rbc volume (higher in m, 47 than f, 42 & more cells) 100s of molecules: ions, nutrients (sugar, lipids, aa, & proteins), main proteins (albumin, globulins, fibrinogen. Rbc/erythrocytes oxygen -transporting cells (7. 5 um- measuring tool/size reference) by hemoglobin w/iron (red) Pick up o2 @lungs & release at tissue capillaries: biconcave shape (+30% sa) no organelles or nuclei (no mito = can"t consume o2) From bone marrow > blood > loose ct (move like amoebas) Diapedesis: circulating ^ leukocytes leave capillaries & venules by actively squeezing between endothelial cells. Granulocytes: w/cytoplasmic granules // n (50-70%) eb. Neutrophils: phagocytize & destroy bacteria, 6-lobed nucleus. Eosinophils: defense response in allergic reactions & parasitic infections.
