ESPM 108B Lecture 18: 18 Epigenetics 2

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Interested in changes that can shape tness-related phenotypes. Can promote plasticity and persistence in heterogeneous environments. Epigenetic effects could have stable transgenerational transmission that in uences phenotypic traits that affect tness, but that are not entirely predicted by the underlying genotype. A lot are rst observations that require detailed follow ups. Variation may be of different relevance to spp. depending on life history/habitat. Methylation-sensitive aflps being replaced by bisulphite sequencing-based techniques using reduced representation next gen sequencing. Speci c single methylation variants (smvs) signi cantly associated w mean max temp. Tend to occur in or near genes, several known to relate to env response. Wild-feeding had higher levels of dna methylation of te. Differentially methylated regions (dmrs) btw smolt and. Bar plot using msap loci to est genetic structure among pops in diff rivers for epi and genetic loci. Epi diff btw methylomes is greater than genetic divergence among closely related pops across 2 river drainages.

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