PSYC3338 Lecture Notes - Lecture 17: Temporal Lobe, Semantic Memory, Episodic Memory
Document Summary
Also apparent in people at high risk for schizophrenia (sibs. , relatives, children of) Depends on medial temporal lobe and hippocampus. Left temporal parietal cortex, superior temporal cortex. Too much dopamine released, maybe a receptor hyposensitivity. Dopamine antagonists relieve symptoms in some people. Thinking got clearer could hold thoughts together and remember from sentence to sentence and communication was more coherent. Having coherent thoughts is an important part of life. But even if you have identical genes, sometimes only one twin will have it. Interaction with environment in utero and out of utero. Notion is that there is a genetic predisposition and an environmental event that precipitated schizophrenia in the presence of a predisposition. Individual proteins in presynaptic and postsynaptic neuron. All have to be just right for synapse to work correctly. Any one of those proteins may be associated with that gene defect. Each synaptic protein is encoded by a specific gene and can be turned on or off.
