BIOL 3210 Lecture Notes - Lecture 2: Alpha And Beta Carbon, Alanine, C-Terminus
Document Summary
Held together by peptide bonds (also sometimes called amide bonds: formed by a condensation reaction (lose a water) between the carboxyl of one amino acids and the amino group of another. Amino acids in the context of a protein are called residues they are the leftovers. Numbering starts from the amino terminus to the carboxyl terminus. Peptide bond between the carbonyl carbon and the nitrogen. **if you are drawing a polypeptide its ncc-ncc- etc . Learn the conformation of the nitrogen and the oxygens. Double partial bond character refers to resonance the peptide bonds resonate between two forms. There is a strong permanent dipole where the oxygen is always partially negative/ nitrogen is partially positive. Because of this, the peptide bond can"t rotate really it"s rigid and almost planar. Almost always found in the trans conformation. The plane of the peptide bond (blue sheets in the image on the slides) the planes meet at the alpha carbon.
