BIOL3030 Lecture Notes - Lecture 16: Shrew, Fetal Hemoglobin, Fetus
9 Oct 2016
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Heart pumps blood through respiratory exchange system then it travels to smaller tissues until eventually it reaches the destination cells. Myoglobin: responsible for carrying oxygen in muscle cell (just 1 molecule not a tetramer) How well they bind to oxygen: oxygen characteristics of the environment, consider, how much oxygen is around and the pressure it is putting on the molecule. Barometer: invented for plumbing purposes (pump water upwards, 150 mmhg or torr for the partial pressure of oxygen, 1 atm=sea level. Partial pressure: 21% of oxygen x atmospheric pressure= partial pressure of oxygen. Compare hemoglobins between species: left shifted=higher affinity, right shifted=lower affinity, more oxygen pressure to get half of the molecules bound to the oxygen. Bohr effect: right shift of an oxygen dissociation curve. Root effect: reducing in low ph conditions the total amount of oxygen that is binded in the hemoglobin, warmer, more acidic=oxygen leaves and becomes available for the oxidation of fuel elevation.
