BIOL 3000 Lecture Notes - Lecture 3: Ribose, Erwin Chargaff, Gc-Content
Document Summary
Levene (1910) tetranucleotide hypothesis protein is genetic material because its structure could be highly variable with its 20 different amino acids. Leven discovered that dna consists of repeating units called nucleotides which contain sugar, base, and phosphate. Chemistry of dna: nitrogenous bases where info is kept, purine, adenine and guanine, pyrimidine, cytosine and thymine, sugar deoxyribose, phosphoric acid (-) charge. Nitrogen bases all ring structures which is part of reason why dna has survived for so long. Purine and pyrimidine are complimentary to each other. Sugar component makes up the backbone of dna. Deoxyribose 2 prime deoxy, lacks o on second hydrogen. Phosphoric acid missing complete bond structure making it have negative charge and attached to five prime. Reactive groups 3 prime oh and 5 prime po4. Described the fundamental ratios of nitrogenous bases in dna. He discovered the four bases are present in equal amounts.