NATS 1670 Lecture Notes - Lecture 33: The Smoking Gun, Lung Cancer, Miscarriage
Document Summary
The class of mechanism of lung carcinogenesis is based on the fact of that carcinogens in the tobacco end up causing dna mutations. Tobacco smoke consists of approximately 60 known components that have adverse biological affects. Adler (1912): primary neoplasm of the lung are among the rarest forms of the disease . 22% of canadians aged 15-19 years old, were smokers in the year 2001. Lung cancer is the leading cause of cancer deaths in the u. s. and canada. In 1992, the u. s. environmental protection agency classified tobacco smoke as the most dangerous cancer-causing agents in humans. In the u. s. , nearly 150,000 people die prematurely each year from tobacco-related cancers and many more from other non-cancer diseases (~500,000) Lung cancer is almost entirely preventable, since the vast majority of cases are due to cigarette smoking. 30% of all cancer deaths are due to smoking. Smoking accounts for ~80% of all cases of lung cancer.