NATS 1670 Lecture Notes - Lecture 10: Helicase, Dna Polymerase, Phosphodiester Bond
3 Dec 2016
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Sc/nats 1670: duplication the molecule of dna must be replicated in and transmitted in each division to. Dna helicase: unwinds the double helix by breaking the hydrogen bonds ensure that all cells contain the same dna; each (cid:498)daughter(cid:499) cell must contain almost identical dna to its (cid:498)mother(cid:499) cell. Starts with the 3(cid:495) end, then adds base pairs 5(cid:495) to 3(cid:495) direction. Dna polymerase is the enzyme that builds complementary pairs using the. Dna polymerase catalyzes the addition of deoxyribonucleotide units to a. Dna polymerase is a template-directed enzyme that synthesizes a product with a base sequence complementary to that of the template. Dna polymerases catalyze the formation of a phosphodiester bond efficiently only if the base on the incoming nucleotide is complementary to the base on the template strand. The new dna chain is assembled directly on a preexisting dna template. The template dna must be bound to primer strand having a free 3(cid:495)
