KINE 3020 Lecture Notes - Lecture 3: Resting Potential, Axon Hillock, Axon Terminal
24 Nov 2018
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Lecture 3, information transmission in the nervous system. To generate a charge, you need to have a potential di erence: na, k, and cl are the main ions involved in this. Within the cell there is lots of potassium, and outside the cell there is sodium and chloride: sodium outside, potassium on the inside, the cell is negative on the inside (-70 millivolts) The resting membrane potential of most neurons is -70mv. Membrane potential is not imbalanced randomly, it is maintained that way using active pumps. The pump that generates this imbalance is the sodium potassium pump, which uses atp. There are also gated ion channels: these gates are voltage gated, meaning certain voltages will open or close it, these gates have di erent selective permeability. To get an action potential, you have to open the gates to allow the change in the membrane potential.
