KINE 3012 Lecture Notes - Lecture 19: Skeletal Muscle, Coronary Artery Disease, Coronary Circulation
6 Mar 2018
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Coronary arteries: they are what profuse the cardiac myocytes with oxygen rich blood, heart doesn"t get nutrients from the blood thats inside its chambers, theres coronary arteries branch o of the aorta. What does the left ventricle have to do when the mean arterial pressure increases: right when you increase mean arterial pressure, you get a reduction in the pressure gradient from the left ventricle to the aorta. If you raise aorta pressure, you get a decrease in gradient, which is what compromises the stroke volume: because of this, you get less blood coming into the aorta, meaning less goes o to the coronary arteries. This means that the heart myocytes will get less oxygen. This could mean that they become oxygen deprived: your heart will try to compensate for this by increasing the contractility of the left ventricle, using the frank starling mechanism.
