KINE 3012 Lecture Notes - Lecture 4: Alveolar Cells, Transpulmonary Pressure, Pneumothorax

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Everything happens in response to change inter pleural pressure, by changing inter pleural volume. Expiration: we relax the diaphragm and intercostal muscles, meaning that the thorax and inter- pleural space get smaller. When is pip not negative: pneumothorax, or when air is in the chest instead of the lung. There is traumatic pneumothorax, where the chest wall gets a hole punctured in it from an accident. Inter-pleural pressure goes up and this causes transpulmonary to go down, which means that recoil is now higher, which means that the lung gets smaller and smaller. 2 things determine lung compliance: the stretchability of the connective lung tissue. When your lung connective tissue is thicker, it has lower compliance, making it harder to expand the lung but easier to close it: surface tension of the water lining the alveoli (the mucus lining). This water tends to want to collapse the lung, and it resists expansion.

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