KINE 2475 Lecture Notes - Lecture 35: Naproxen, Adverse Drug Reaction, Losartan

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Background: medication conditions, allergic reaction & nature of allergic rxn, medication history (rx, otc, herb, vitamins) Patient"s concern & chief complaint: explain the condition, why is patient having symptoms. Disease where monosodium urate monohydrate (msu) crystals deposit in joints, soft tissues such as cartilage, tendons, or in renal tissues of glomeruli. List goals of therapy (parameter, desired value, change, timeframe: prevent recurrence in the next 6-12 months, terminate acute attack of arthritis. Levodopa: alcohol, cyclosporine, cytotoxic chemo, diuretics (thiazide, loop, niacin, salicylates, tacrolimus, atherosclerosis, chronic kidney, glomerular, renal disease, diabetes, hyperlipidemia, hypertension, ischemic heart disease, metabolic syndrome, obesity, diet. Assessment of alternatives: asymptomatic stage, acute gouty arthritis, nsaids, colchicine or oral corticosteroids are first. Should be initiated within first 24 hrs of acute gout attack onset: colchicine: initially 1. 2mg is given, then 0. 6 mg 1 hr later. A prophylactic dose of 0. 6mg od-bid can be started 12 hrs later: nsaids: reduce pain & swelling.

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