KINE 2475 Lecture Notes - Lecture 20: Quinolone, Peptide, Metolazone

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Chronic inflammation: ckd-mineral & bone disorders (cdk-mbd) include abnormalities in: However ineffective as kidney function declines: management of anemia includes administration of: Regular iron supplements to maintain hb concentrations (& prevent transfusions) Higher risk of cv events when hb > 11g/dl (110g/l; 6. 83mmol/l: management of ckd-mbd (mineral bone disorders) includes: Calcimimetic therapy in dialysis: statins are indicated for primary prevention in those with non-dialysis dependent ckd. Assess: serum creatinine, gfr, creatinine clearance, presence of albuminuria, serum potassium concen. Assess frequently in patients with ckd & hf: hemoglobin concentrations. Iron indices (transferrin saturation & ferritin)- for patients on esa. Assess transferrin saturation (tsat) & ferritin at least every 3 months: blood pressure. Plan: drug therapy recommendations- including dose, route, frequency & duration, patient education: lifestyle modifications, medication administration, self-monitor of symptom & blood pressure targets, medications to hold on sick days if vomiting or diarrhea (acei/arb)

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