KINE 2011 Lecture Notes - Lecture 3: Adenine, Guanosine Diphosphate, Intermembrane Space
19 Sep 2016
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Anaerobic not efficient, most energy is still in pyruvate. Break down 6c glucose molecule into 2 pyruvate. All e- are carried into the final step. Mcardle s disease: absence of enzyme involved in first step of glycogen to glucose conversion. Lose 1c in the form of co2 (lost in form of cardiorespiration/exhaled) 8 separate reactions directed by enzymes from the mitochondrial matrix two carbons are sequentially removed from the 6c citrate molecule -> converted back to the 4c oxaloacetate, ready to accept a new acetyl-coa. These 2c are converted into 2 molecules of co2. These 2 co2 as well as the one produced during pyruvate decarboxylation, pass out of the mitochondrial matrix -> out of the cell -> blood. The o2 used to form these co2 molecules is coming from these molecules involved in the cycle, not from the free o2 supplied from breathing. Hydrogen atoms are also removed, these h atoms will then enter etc.
