KINE 1020 Lecture Notes - Lecture 12: Oxidative Phosphorylation, Osteopenia, Sarcopenia

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Aging extent of the of msk + cv health depends on level of physical activity and genetics. As activity decreases, the reductions in physiological function are more substantial. Sarcopenia loss of muscle mass associated with aging. Osteopenia loss of bone mass associated with aging. You need to maintain a baseline of fitness for everyday living . *in relation to that disability threshold on the graphs from the slides. Factors leading to loss of muscle mass/strength: decrease in size. Muscle size peaks around 24yrs, maintained up to 50yrs (10% reduction) B/w 50-80yrs, additional 30% degeneration becomes a total of 40% This loss is mirrored by a of fibre # Atrophy at fibre level (~25% to size of type ii fibres, compared to no change in type i: fibre type composition. Originally thought that type ii fibres convert to type 1 but it"s now accepted that you lose both equally. *size of type ii decreases, but they both disappear equally*

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