KINE 1020 Lecture Notes - Lecture 8: Osteopenia, Cardiac Muscle, Skeletal Muscle
Document Summary
Healthy muscles allow a person to move freely and to keep the body responsive and strong. Who: worldwide msk disorders are among reasons why people take time off work (lower back pain #1) Msk: limited body structure, activity limitations, life limits. Incidence greatest in 3rd decade, increases until age 60-65. At age 80, 30% osteopenia and 70% osteoporotic. Skeletal muscle (striated/voluntary), cardiac muscle and smooth muscle (nonstriated) Actin/myosin interaction = contraction (first need energy, calcium and alignment of proteins) Mybpc is located in the middle of each half of a-band. It binds to myosin tail region and maintains thick filaments in bundles of 200 to 400 molecules. Latent period is 1-2 msec, contraction 40-120 and relaxation 50-200. Contraction time depends on myosin type and mybp-c. Motor unit recruitment, frequency of stimulation, optimal muscle length and type of contraction influence for generation by whole muscles. Glycolysis is associated with a -642 kcal/mole (exergonic)