HIST 3791 Lecture Notes - Lecture 45: Streptococcus Pyogenes, Streptococcal Pharyngitis, Antibiotic Prophylaxis
Document Summary
Wound infections: may be traumatic, surgical, secondary to a bite (animal or human) Source of infection: own normal flora, environmental (soil), oral flora of animal, other infected individual (fomites, hands) Factors contributing to wound infections: dose and virulence of organism, physiologic conditions of wound (ie necrosis, blood supply, poor oxygenation), general health and condition of patient. Etiologic agents vary depending on site and type of wound. How to prevent wound infections: sterile technique, antibiotic prophylaxis, clean and flush traumatic wounds, use vaccines, surgery to remove debris, foreign matter, dead tissue-do drainage. Use antibiotics guided by site and lab results. Upper respiratory tract: nose, pharynx, sinuses, middle ear, epiglottis. Lower respiratory tract: larynx, trachea, bronchial tubes, alveoli. Several anatomical defenses against airborne pathogens: nasal hairs, cilia, mucous, ciliated mucous membranes of throat trap particles greater than 4-5 um, lymphoid tissues (tonsils and adenoids) Pharyngitis (sore throat) and tonsillitis-most causes are due to viruses, common cold .
