HIST 3791 Lecture Notes - Lecture 35: Pravastatin, Simvastatin, Atorvastatin
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Placebo x 4 mos, simva 20 mg vs. Simva 40 mg x 1 mos, simva 80 mg. 35 - 75 years, history of cad/mi (not recent) 2. 7 vs 2. 4 p=. ns 5. 6 vs 5. 3 p=ns. Scandinavian simvastatin survival study group randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the scandinavian. Sacks fm, pfeffer ma, moye la, et al the effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. The long-term intervention with pravastatin in ischaemic disease (lipid) study group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels n engl j med 1998;339:1349-57. Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes. The effects of atorvastatin when introduced early after an acute coronary syndrome jama 2001;285:1711-1718.
