CRIM 2653 Lecture Notes - Lecture 50: Elastic Fiber, Endothelium, Atherosclerosis
23 May 2020
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Document Summary
You can prevent atherosclerosis 90% of the time. Athelerosclerosis is the critical player in length of life significant difference in ethnicity. Athlerosclerotic plaque, fibrous complicated plaque to narrow lumen of vessel to make it difficult to open and constrict the vessel. Disease of large and medium sized arteries, not veins. Chronic disease, long time to develop takes a lifetime to develop mostly 63 yrs old caucasian, 67 for females to have problems asian need to be careful for heart, go to. Inner=single layer of cells, difficult to see= endothelial cells. Media give vessel elasticity blood pressure goes up in systole and down in diastole, so need to expand and come back. Athelerosclerosis destroy media muscles and vessel and loses its elasticity and compliance. Between adventitia and media, is elastic tissue, between media and intima you have more elastic tissue endothelial cells produces all these elastic tissue.
