CHEM 2020 Lecture Notes - Lecture 5: Telomerase Reverse Transcriptase, Alkane, Thermodynamics

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24 Aug 2020
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Alknae: fluoroctclohexane < isopropycyclohexane < tert butyl cyclohexane, disubstituted example. As before, what"s axial becomes equatorial and vice versa after a chair flip. Be on the lookout for interactions between substituents as well. Chemicla reactions: mechanism, thermodynamics, kinetics, selectivity, reaction intermediates, most important concepts: Kinetic selectivity reaction intermediates: case studt approach. A mechanism is the stepwise description of the formation and breaking of bonds in the correct sequence to give the observed products. Mechanisms are postulated to be consistent with observation, with the thermodynamics and the kinetics. Thermodynamics studies the energy changes involved, the stability of products, the equilibria governing reactions and how they will vary with conditions. Kinetics studies the rates of reactions, which product(s) form(s) fastest & how the rates will vary with conditions. The reactions (ch4 and cl2) contain only c h and cl cl bonds. The products contain c cl and h cl bonds, fewer c h bonds and no cl cl bonds.