BIOL 4310 Lecture Notes - Lecture 13: Ac Propulsion Ebox, Zebrafish, Clock Signal

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Teleosts compared to humans due to evolution: differences mo in fish compared to drosophila nad mammals. In fish: all three have are photosensitive and have a rhythmic mo and produce rhythmic activity such as cap or hormone production: the three structures are loosely coupled so each region will function independent. In mammals: highly coupled and centralized as the scn is the master clock. Loss of rhythmicity indi(cid:272)ates that it"s the driving (cid:272)lo(cid:272)k. It depends on the species of fish being tested: this indicates that the pineal gland can function as a circadian clock, anatomy of pineal gland: In fish: located dorsally on top of the head and its photosensitive. In mammals: its located in the center involved in the circadian but plays a smaller role because it cant receive direct photoinformation. In mammals they are not: the autonomous peripheral clocks throughout the body are controlled by melatonin rhythmic release from the pineal gland in the brain they express melatonin receptors.

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