BIOL 2021 Lecture Notes - Lecture 22: Cancer Stem Cell, Hematopoietic Stem Cell Transplantation, Adult Stem Cell
Document Summary
Once cell (from fertilized egg) man cell types. 7-1: making diff proteins i. e. structural ion channels, signal proteins, enzymes, gene regulatory proteins. 7-29, nuclear transplantation: reprograms; the skin nucleus; the nucleus of the skin cell now acts like an embryonic nucleus; there is no change in the. Dna; fertilized egg makes a blastula (hollow ball of cells), which turns into a gastrula cells are now different! Blastomere cells are totipotent: have potential to make all cell types in the final adult organism; they do differentiation: cell specialization. Usually permanently stop dividing; often in g0 stage of the cell cycle. 22-3): new differentiated cells usually come from stem cells; properties: not terminally differentiated, can divide without limit, daughter cells can differentiate or remain a stem cell = self-renewal. Examples of adult stem cells: epidermal epidermis of skin intestinal epithelial of gut hemopoietic make blood cells and done in bone marrow.