BIOL 2021 Lecture Notes - Lecture 4: Lipid Bilayer, Glycerophospholipid, Phosphatidylethanolamine

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Plasma membrane: encloses the cell, defines its boundaries, and maintains the essential differences between the cytosol and the extracellular environment. Organelles in animal cells have similar membranes that separate the cytosol from the contents of the organelle. Separates inside from outside environments: cell vs. environment, organelle vs. cytosol (in animal cells) Maintain ion gradients using channels and transport proteins. Signaling functions: receptors in the plasma membrane. Cell membrane consists of lipid and protein molecules that are held together by non-covalent interactions. Protein to lipid ratio is 50:50 (by weight) Lipids are fatty molecules that are amphiphilic: both hydrophilic and hydrophobic. Lipid bilayer: provides the basic structure for all cell membranes and is composed of 2 leaflets. Lipid bilayer is 5nm thick and provides the basic fluid structure of the membrane and serves as an impermeable barrier to the passive of most water-soluble molecules.

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