BIOL 2021 Lecture Notes - Lecture 6: Protein Targeting, Curare, Membrane Transport

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tealminnow441

26 Jan 2017

School

York University

Department

Biology

Course

BIOL 2021

Professor

Patricia Lakin- Thomas

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Document Summary

1) neurotransmitter destroyed by enzyme: ex: acetylcholinesterase destroys ach. 2) transmitter taken up by pre-synaptic cell = recycling (endocytosis) We have 2 kinds of synapses: 1) drugs at synapses. Curare: blocks acetylcholine receptors at skeletal muscles (nmj) causes muscle paralysis tranquilizers: bind gaba receptors and increases the response to. Prozac antidepressant: inhibit the reuptake of serotonin increase synaptic transmission in cns. Chapter 12 compartments and protein sorting fig 12-2 tem of liver cell lumen: interior of organelle. Cytoplasm: cytosol + extra nuclear organelles function of organelles: 1) increase surface area of membranes, 2) divide cytoplasm into functionally specialized spaces function depends on protein. Organelles can be divided into 4 families: 1) nucleus and cytosol. Connected by nuclear pores: 2) secretory/exocytotic organelles. Connected to eachother by vesicle transport: 3) mitochondria, 4) plastids (chloroplasts + others) fig 12-4b topological relationships topology = math of holes, maps and knots. Lumen of er, golig, endosomes are equivalent to being outside the cell.

Related Questions

The junction specialized for the transmission between a neuron and another cell is called a (1) _____ ______. Usually, the signal being sent to the receiving cell is carried by chemical messengers called (2) _____. (3) _____ is an example of this type of chemical messenger, which diffuses across the synaptic cleft, combines with protein receptor molecules on the muscle cell membrane, and soon thereafter is rapidly broken down by enzymes. At an (4) ____ synapse, the membrane potential is driven toward the threshold value and increases the likelihood that depolarization and an action potential will occur. At an (5) ____ synapse, the membrane potential is driven away form the threshold value, and the receiving neuron becomes hyperpolarized and is less likely to achieve an action potential. A specific transmitter substance can have either excitatory or inhibitory effects depending on which type of protein channel it opens up in the (6) ____ membrane. (7) ____ are neuromodulators that inhibit perceptions of pain and may have roles in memory and learning, emotional states, temperature regulation, and sexual behavior. (8) ____ ________ at the cellular level is the moment-by-moment tallying of all excitatory and inhibitory signals acting on a neuron. Incoming information is (9) ____ by the cell bodies, and the charge differences across the membranes are either enhanced or inhibited. Some narrow-diameter neurons are wrapped in lipid-rich (10) _______ produced by specialized neuroglial called Schwann cells; each of these is separated from the next by a(n) (11) ________ ________ - a small gap where the axon is exposed to extracellular fluid. A (12) ____ is an involuntary sequence of events elicited by a stimulus. During a (13) _______ ________, a muscle contracts involuntary whenever conditions cause a stretch in length; many of these help you maintain an upright posture despite small shifts in balance. Imbalances can occur at chemical synapses; a neurotoxin produced by Clostridium tetani blocks the release of GABA and glycine, thus freeing the motor neurons from (14) _____ control, which may cause tetanus â a prolonged, spastic paralysis that can lead to death. A. Excitatory H. Stretch reflex B. Inhibitory I. Summed C. Myelin J. Neurotransmitters D. Chemical synapse K. Postsynaptic E. Synaptic integration L. Endorphins F. Exposed node M. Acetylcholine (ACh)

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BIOL 2021 Lecture Notes - Lecture 6: Protein Targeting, Curare, Membrane Transport

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