BIOL 1000 Lecture Notes - Lecture 4: Golgi Apparatus, Intermediate Filament, Endoplasmic Reticulum

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4 Oct 2015
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Organelle: 4 criteria: specialized function, membrane bound, only in eukaryotes. Same phospholipids bilayer for different organelle that"s why fussion of vesicles isn"t an issue. What items need to get in and out of the nucleus: transfer factor need to get in the nucleus. Proteins need signals to get in and out of the nucleus. Chromatin: dna wraps around proteins called histones, gives it the compact structure to fit in the nucleus. Inside the lumen contains chaperon proteins that help to fold the proteins: some ribosomes will always be free; they wont always be bound to the membrane, specific amino acids. Smooth er: lipid and steroids, regulates calcium concentration in the cell, metabolism carbohydrates, can also metabolise certain drugs inside the cell. Polyribosome structure: helps speed up the protein synthesis. Vesicular trafficking very highly ordered even though it looks chaotic in terms of process. Vesicles leaving the er fuses with the golgi body.

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