PS268 Lecture Notes - Lecture 14: Cyclooxygenase, Circulatory System, Phenylephrine
Document Summary
Chapter 14: new drug discovery and drug testing/clinical trials. Over-the-counter (otc) drugs: drugs available to the public without the requirement of a prescription must have a greater margin of safety than prescription drugs. Prescription drugs: drugs available to the public only when approved by a medical professional and dispensed by a licensed pharmacist. First passed in 1920; last updated in 1985. Cures and treatments for serious diseases cannot be advertised to the. Ingredients in products must be displayed general public. Getting a new drug to the marketplace: animal and human (clinical) testing. Novel synthesis: synthesized in a chemistry lab. Ethnobotany/isolation/purification: an organism (plant, animal, bacteria, etc. ) makes it, and its purified in the lab. Repurposing/repositioning: the drug already exists and has a medically proven purpose, but you think it could treat something else as well. Chemical name: compete chemical description of the molecule. Generic name: official (legal) name fluoxetine.
