KP222 Lecture Notes - Lecture 9: Membrane Technology, Skeletal Muscle, Resting Potential
31 Jan 2019
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Document Summary
Resting potential: transmembrane potential of resting cell. Grade potential: small, communicate over short distances, temporary localized change in resting potential. Action potential: large electrical impulse, produced by graded potential, communicate over large distances. Synaptic activity: release neurotransmitter, extend graded potentials. Cholinergenic synapses: any synapses that releases each, all nmj with skeletal muscle bres, many synapses in cns, all neuron-to neuron synapses in pns, all neuromuscular and neuroglandilar junctions of ans parasympathetic division. Can be excitatory or inhibitory depending on receptor subtype: nicotinic or muscarinic. Enzyme that breaks down ach: into acetate and choline. Choline can be reabsorbed in pre-synaptic terminal. Excitatory postsynaptic potential (epsp: skeletal muscle, some regions of the brain, picture. Inhibitory postsynaptic potential (ipsp) cardaic muscle, some glands. Derived from amino acids: catecholamines: derived form tyrosine, dopamine, norepinephrine (noradrenalin) & epinephrine (adrenalin) Adrenergic receptors (usually slow responses: serotonin: derived from tryptophan, histamine: derived from histidine. Released from neutrons in: cns dopamin, serotonin, histamine.
