KP222 Lecture 5: KP222 Lecture 5

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Energy is released from ion di usion: kinetic energy from a gradient drives a pump. Di usion results from proviso active transport of the ion. Na+ down its gradient provides energy: drives glucose movement against gradient. Sodum-proton exchange: examples of countertransport , na+ down its gradient provides energy. Icf/ecf concentrations di er because of active transport. Water moves to dilute more concentrated side. Is the pressure that would be applied to stop any water movement. Isotonic when it doesn"t alter cell volume (ie. saline) Solutions are initially iso-osmotic but not isotonic. Osmolarity deals with toal concentrations of solutes (both penetrating and non- penetrating) Tonicity is only the concentration of non-penetrating solutes. Always in reference to the extracellular non-penetrating solute concentration relative to the cells non-penetrating solutes. Slightly switch focus from in and out of cell. Acts as an anchor and provides physical support. Solutes are pumped into the interstitial uid. Osmotic pressure of the interstitial uid increases.

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