BI236 Lecture Notes - Lecture 20: Histone Acetyltransferase, Histone Deacetylase, Gene Duplication
Document Summary
Regulation is an important aspect of gene expression. Selective gene expression allows cells to be efficient, synthesizing only what is needed for each cell type: some genes: constitutive genes (needed all the time) Include ribosomal genes and genes encoding the enzymes of glycolysis: regulated genes: proteins not constantly required. The 1st understanding of gene regulation came from bacteria. Multicellular eukaryotes are composed of numerous specialized cell types. Multicellular eukaryotes mixture of specialized or differentiated cell types. Differentiated cells : produced from groups of immature, non-specialized cells: e. g: cells of the early embryo produce all the cell types that make up the organism. Distinguished from each other based on structure and function: differential gene expression plays a central role in creating differentiated cells. Eukaryotic gene expression is regulated at 5 main levels. Almost all cells retain the same complete set of genes.
