BI110 Lecture Notes - Lecture 8: Neuron, Sigma Factor, Rna Polymerase Ii

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Believed that rna (not dna) was the original info storage molec in earliest forms of life on earth. Rna used in key cellular processes, including dna replication, trans x2. Experiments have shown that rna can evolve over time & act as a catalyst. 5" end of dna strand is typically monophos, the 5" end of an. Use dna template to create a complementary rna strand. Template dna read 3"-5", so that you can synthesize rna in the 5" to 3" direction. Non template = not used as the template, used as the coding strand (rna coding should match up to this strand except u vs. Synthesized in a 5"-3" direction by rna polymerase (added on to the 3" end) Terminator is always at the end of the 5" on the dna. Most genes are transcribed only at certain times, in certain conditions, or in certain cell types.

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