Rehabilitation Sciences 3060A/B Lecture 11: Osteoporosis
1 Jun 2016
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Document Summary
Characterized by : low bmd, a deterioration of the micro-architecture of bone tissue. This leads to bone fragility results in fracture risk. Silent disease": not manifested until fracture, asymptomatic until fracture height. In quebec (2008: 80% of fractures in women > 50yr directly related to osteoporosis, 80% of these never diagnosed with or treated for osteoporosis. In u. s = > 10 million osteoporosis (hip: most of the economic burden from osteoporosis due to osteoporotic. > 60% of admissions to in-patient rehab. Because of an imbalance in the bone remodeling process: bone . " by osteoblasts resorption" (removal) by osteoclasts is favoured over bone: resulting in a loss of bone mass. Age-related osteoporosis: bone formation via osteoblasts ( ) and via osteoclasts ( ) Post menopausal osteoporosis: bone formation via osteoclasts ( ) Most evident in trabecular bone (5 20% of spinal trabecular bone mineral lost yearly) thus, often see spinal fractures in early post menopause.
