Rehabilitation Sciences 3060A/B Lecture Notes - Lecture 10: Flor, Bronchiectasis, Exhalation
Document Summary
Chronic pulmonary dysfunction and anaesthesia in health care. Etiology (many diseases = many different causes) broad summary only. Any person that has to receive anaesthesia is at risk of developing these adverse effects. If you have a chronic pulmonary disorder, it can have an even bigger impact. Respiratory failure (usually defined as the need for mechanical ventilatory support) Anaesthesia impairs central respiratory regulation and tone of respiratory muscles. Anaesthesia works by affecting the cns and will influence muscles. If cns is affected, those muscles involved in respiration can be influenced. At high doses, some anaesthetics globally depress muscular activity and reduce the respiratory effort. Release of inflammatory mediators by some anaesthetic agents produces bronchospasm, resulting in hypoxia, hyperinflation and air trapping. Subset population that will develop asthma from sensitivity to medication (i. e. aspirin) Dry anaesthetic gases and prolonged mechanical ventilation may impair normal mucociliary mechanism and lead to atelectasis from mucus plugs.