Psychology 2220A/B Lecture Notes - Lecture 6: Agonist, Neurotransmitter, Deep Brain Stimulation

• School: Western University
• Department: Psychology
• Course: Psychology 2220A/B
• Professor: Jody Culham

Document Summary

Drug actions: drugs can act at any stage of synaptic transmission, agonists: drugs that increase the effectiveness of synaptic transmission, antagonists: drugs that decrease the effectiveness of synaptic transmission. Important point: agonist/antagonist excitatory/inhibitory: agonist increased nt effect if nt is excitatory increased postsynaptic excitation (epsps) post-synaptic neuron more likely to fire ap if nt is inhibitory increased postsynaptic inhibition (ipsps) Post-synaptic neuron less likely to fire ap: antagonist decreased nt effect if nt is excitatory reduced postsynaptic excitation (epsps) Post-synaptic neuron less likely to fire ap if nt is inhibitory reduced postsynaptic inhibition (ipsps) Post-synaptic neuron more likely to fire ap. Antagonist likelihood of firing ap up likelihood of firing ap down i c g r e a m a t t l u. G g e likelihood of firing ap down likelihood of firing ap up e s p a n y.