Psychology 2220A/B Lecture 12: Lecture 12 - Neurodevelopment

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Brain development: cns develops from ectoderm (outside layer) based on signals form mesoderm (middle layer) Neural tube: ectoderm (outside), mesoderm (middle), endoderm (inside) Neural plate folds into a neural tube which becomes spinal cord & part of brain. Spina bi da = an incomplete closure of the tube. Evo-devo: earliest stages of development are more generic initial embryo has ability to develop into basically anything. Speci c features disappear as they are unneeded (gils) Cell birth & differentiation: stem cells line ventricles (capability to differentiate into any cell) Gene expression determines the type of cell. Gene expression determined by local hormonal environment. Neurons are born / minute at the peak of prenatal development. Inner layers form rst (6 then 5 then 4) Pia mater at top of parking lot. Lopodia are attracted to cell-adhesion molecules (cams) Different chemicals either repel or attract growth cones. * retrograde going from where cell was damaged back to cell body.

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