Physiology 3120 Lecture Notes - Lecture 5: Peripheral Chemoreceptors, Blood Gas Tension, Chronic Obstructive Pulmonary Disease

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Receptors send input signals to central controller that then sends signals to respiratory muscles to change/maintain respiration. Respiratory muscles send negative feedback to receptors to stop pathway. Rmr from second lecture that respiratory muscles are diaphragm, internal and external intercostals. Neurons that contribute to respiration in those 4 areas. Damage to this area causes person to take in small gasps of air. Some textbooks leave this out since do not know what it does exactly in healthy people. In people with damage to pneumotaxic center, this area compensates so that person does not take in short gasps of air and can take in long inspirations. Inspiratory area allows for regular breathing by sending aps to respiratory muscles for ventilation. When pneumotaxic area inhibited, apneustic center comes in to prolong inspiration. So info on partial pressures of gases in blood collected by receptors. Receptors then send signals to central controller based on that info.

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