Physiology 3120 Lecture Notes - Lecture 14: Synaptic Plasticity, Neuromodulation, Nmda Receptor
5 Apr 2018
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If neuron # equilibrium potential of chloride, there is nothing an additional ipsp can do but keep it at rmp. As depolarization continues, there is an equilibrium potential of sodium, but that is past the point of action potentials are generated. If you suppress the neuron from making action potentials, epsp would continue to depolarize the neuron until it reached the equilibrium potential of sodium. Note: the cell is always leaky to potassium what brings it back to rmp. This defines the information processing of the neurons, defines how the neuron responds to its stimuli: stimuli = epsp, ipsp. Need many epsps to generate action potentials. Two ways to summate: spatial summation, temporal summation. Note: both methods of summation are occurring at the same time! Spatial summation: summing of synaptic potentials (ipsp, epsp) at different spatial locations on a neuron. Temporal summation: summing of synaptic potentials at a single synapse.
