Physiology 3120 Lecture Notes - Lecture 4: Ileocecal Valve, Centroacinar Cell, Chymotrypsinogen
2 Apr 2017
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Ileocecal valve: ensures separation of small and large intestine so that small intestine is low in bacteria # (point where you vomit from) Appendix: stores bacteria & keeps it safe: normal flora, mostly anaerobic bacteria. Haustra: circular regions that"s helpful for mixing the chyme (allows it to optimally interact with bacteria and betters water absorption) Gastroileal reflex: presence of food in the stomach stimulates the opening of the ileocecal valve ii. Haustral churning: mixing of large intestine contents from one haustra to the next, optimal absorption (nutrients & water) iii. Peristalsis & mass peristalsis: unidirectional movement of lumen contents out of the large intestine, mass peristalsis stronger contraction. Both exocrine and endocrine function, review endocrine secretions (insulin, glucagon and somatostatin) Exocrine secretions are secreted into the duodenum. Acinar cells: end part of ducts: secrete enzymes (zymogens, zymogen are proenzymes that must be cleaved to be activated. Ductal cells: line duct: secrete hco3- and h2o.
