Physiology 3120 Lecture Notes - Lecture 14: Persistent Vegetative State, Cranial Nerves, Evoked Potential

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Ascending (brainstem up to the cortex) reticular (part of this system) activating (wake up cortex) Stimulate certain brainstem areas: wake up sleeping animal. Ascending reticular activating system: also descending effects reticulospinal sends ipsps, i. e. to alpha mns, proximal muscles postural muscles (particularly the leg muscles that hold proximal muscles in rem your posture against gravity) If you make a decerebrate lesion through ascending connections, animal will be. Spinal cord give rise to mid brain pons medulla. Rostral pons caudal midbrain ascending arousal system for consciousness paralyzed bc no motor pathway comes through animal is also unconscious. ** 5 different transmitter systems that are coming from this particular region of the brainstem. Coma: bilateral lesion of rostral brainstem i. e. decerebration, bilateral lesion of cerebral cortex i. e. hypoxia, hematoma. No movement arms, legs, speech: ascending connections are still present, neurons on the motor cortex are severed, no commands getting through paralyzed. One patient dictated memoir one letter at a time by blinking.

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