Physiology 2130 Lecture Notes - Lecture 1: Lipid Bilayer, Extracellular Fluid, Fluid Compartments

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Homeostasis, membrane transport and the excitable cell- dr. mclean. The study of the normal functioning of a living organism and its component parts. The ability of the body to maintain a relatively constant internal environment. Cells are surrounded by extracellular fluid (interstitial fluid and plasma) Intracellular fluid =28 l (67% of tbw: extracellular fluid =14 l (33% of tbw) Interstitial fluid =11 l (26. 4% tbw: plasma 3 l = (6. 6% tbw) Concentration of ions in cell: salty banana in a glass of milk. High [na+], [cl-] and [ca+] outside the cell and high [k+] inside the cell. Communication of the cell with its environment. The interaction of the cell with its environment. A form of passive diffusion (does not require energy) Movement of particles from an area of high concentration to an area of lower concentration. Diffusion of fat soluble molecules through lipid bilayer. Like dissolves like (lipid bilayer dissolves fat soluble molecules)

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