Physiology 2130 Lecture Notes - Lecture 8: Distal Convoluted Tubule, Renal Corpuscle, Macula Densa

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Kidney function: most important function is the regulation of salt and water balance in the body, removal of waste is a function, though less important, 7 major functions of the kidney. Regulation of extracellular fluid volume and blood pressure. Regulation of osmolality: maintain ion balance, maintenance of body ph. Kidney anatomy: 2 kidneys - one on each side of the spine, posterior side of the abdomen - outside of the abdominal cavity. Innermost, hollow centre of the kidney where urine collects: cortex, tissues which lies on top of the medulla, medulla, outermost tissue of the kidney, nephrons, filtering units, throughout the medulla and cortex. Specialized, leaky group of fe(cid:374)estrated capillaries which lie i(cid:374)side bow(cid:373)a(cid:374)"s capsule. Fenestrations are so large that anything (except blood cells) can filter into. Juxtaglomerular apparatus (jga: the junction of the late ascending limb of the loop of henle which passes between the efferent and afferent arterioles near the renal corpuscle entering.

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