Physiology 2130 Lecture Notes - Lecture 5: Conformational Change, Smooth Muscle Tissue, Neuromuscular Junction

• School: Western University
• Department: Physiology
• Course: Physiology 2130
• Professor: Christine Bell

Document Summary

Skeletal (striated) muscle: used primarily for voluntary motion (examined in this lecture) Smooth muscle: found in the walls of the blood vessels, airways, various ducts, urinary bladder, uterus, digestive tract. A whole look at the structure of muscle. Bundles of fasciculi make up the whole muscle. Fasciculi are made up of muscle cells/fibres. Each myofibril contains a sarcomere, made up of thick/thin filaments: contain actin (mostly), with some troponin and tropomyosin. Whole muscle is made up of many fasciculi. Each fasciculus is surrounded by white connective tissue known as perimysium. Fascicles are made up of individual muscle cells (known as muscle fibres) Cylindrical bundles of myofibrils within muscle cells: myofilaments are contained within myofibrils: two types. Sarcolemma: muscle cell membrane which can transmit an action potential, has t-tubules. T-tubules (transverse tubules): projections of the sarcolemma into the cell body, which allows for the action potential to extend down into where the contractile proteins are located.