Physiology 1021 Lecture Notes - Lecture 1: Renal Corpuscle, Renal Pelvis, Renal Cortex

• School: Western University
• Department: Physiology
• Course: Physiology 1021
• Professor: John Ciriello

Document Summary

Where the filtered fluid is processed: categorization of nephrons based on positons within the kidney and some anatomical differences. Filtered load x = [x] plasma x gfr: renal handling is then determining how much of that substance gets into the urine and hypothesizing how that substance was handled. Transport mechanisms: cells of the tubule, the tubule of the nephron is made of a single layer of epithelial cells. The membrane facing the inside of the tubule, or the lumen, is called the luminal membrane. Channels are small protein lined pores that permit specific molecules through them. This movement is passive (no atp required) and is driven by a concentration or electrochemical gradient: transporters, uniporters: permits movement of a single molecule through the membrane. These are protein carriers that bind to molecules: symporters (co-transport): permits the movement of 2 molecules in the same direction across a membrane. At least 1 molecule must move down its concentration gradient to move both molecules.