Pharmacology 2060A/B Lecture Notes - Lecture 10: Antihistamine, Statin, Spasm

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Pharmacology 2060b module 10: adverse drug reactions and medication errors. Adverse drug reactions (adrs) are the unintended and undesired responses from drugs. Adverse drug reactions are an enormous societal health problem. Canadian research suggests that 7. 5% of hospital admissions in canada are attributed to adverse drug reactions. This represents 185 000 people per year. Adverse drug reactions can include: side effects, drug toxicity, allergic reaction. Idiosyncratic reaction: carcinogenic effects, mutagenic effects, teratogenic effects. Side effects are secondary to the main therapeutic effect of the drug and are unexpected. Side effects occur at normal therapeutic doses and are often unavoidable. Side effects are often due to poor specificity or selectivity of the drug. I. e antihistamines act by blocking h1 histamine receptors to prevent the symptoms of allergy (i. e. runny nose, watery eyes) Side effects include drowsiness, dry mouth, and urinary retention.

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