Pharmacology 2060A/B Lecture Notes - Lecture 14: Temporal Lobe Epilepsy, Partial Seizure, Jamais Vu

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Epilepsy is a neurological disorder that produces brief disturbances in the normal electrical activity in the brain: characterized by sudden, brief seizures, the nature and intensity of which vary from person to person. Seizure: sudden alteration of behaviour caused by cns dysfunction; sudden and transient. Epileptic seizure: seizure caused by primary cns dysfunction due to excess depolarization and hypersynchronization of neurons. Non-epileptic seizure: seizure-like episode that"s not the result of abnormal electrical activity in the brain. Status epilepticus: single continuous epileptic seizure of duration < 30 min. or frequent seizures without recovery of awareness in between; emergency status. Types of seizures: focal/partial seizures, arise in one area of the brain, the terms focal and partial seizure are interchangeable, 2 types of focal/partial seizures: simple and complex. Generalized seizure: have a bilateral, diffuse onset, seeming to arise from all areas of the brain at once, 5 different types of generalized seizures: absence, tonic/clonic, myoclonic, tonic and atonic.

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